The global nucleic acid isolation and purification market revenue was around US$ 2.95 billion in 2022 and is estimated to reach US$ 5.51 billion by 2031, growing at a compound annual growth rate (CAGR) of 7.2% over the forecast period from 2023 to 2031.
Nucleic acid isolation and purification is a common first step in genetic and genomic investigations in the isolation of genetic material from the sample matrix. The first step in the extraction and separation of nucleic acid is the disruption of the cellular structures that contain the genetic material, such as the ribosomes, nuclei, bacteria, and viruses. Usually, this is accomplished by adding a suitable detergent, causing mechanical disruption, and heating the cells.
Market Driving Factors
The increasing prevalence of STDs (Sexually transmitted diseases) boosts the market growth. Nucleic acid isolation and identification processes can be used to diagnose almost all STDs, which is causing the industry to rise. According to the World Health Organisation (WHO), more than a million sexually transmitted illnesses are contracted every day worldwide. Approximately 500 million people worldwide have the herpes simplex virus (HSV), and 290 million women are infected with the human papillomavirus (HPV).
Laboratory automation is rising creating a positive impact on the market. Automation is the transfer of laboratory tasks from people to machines. DNA analysis is a recurring process that may be automated, whereas screening evidence is a one-time occurrence. The robotic systems enable the scientist to work with more samples, examine more plates, and take longer breaks from the procedure. A laboratory must be ready to spend an excessive amount of time validating and training analysts to migrate from manual to robotic analysis to lower the backlog and boost productivity.
The price of automated and kit-based equipment for nucleic acid isolation and purification is higher than that of conventional methods. Thus, the higher cost impedes the market.
Regional Analysis
North America dominated the market and is anticipated to increase at the highest CAGR throughout the projection period. This can be attributed to the rapid technological development, rising biotechnology and healthcare R&D spending, environmental testing, and expanding usage of nucleic acid isolation in food production. The presence of organisations like the Food Safety and Inspection Service (FSIS), and the Food and Drug Administration (FDA) which oversee processed food safety, supports the region's growth.
Asia-Pacific is estimated to dominate the market over the forecast period. China holds the largest share in the region owing to the rapid growth in the preparation of RNA and DNA libraries for next-generation sequencing. Additionally, numerous life science laboratories in China are experimenting with nucleic acid purification, which is fostering market expansion.
Segmentation Insight
Method Insight
The magnetic bead-based isolation and purification segment dominates the market over the forecast period. This is due to its use of high-capacity paramagnetic particles for nucleic acid isolation, which offers higher yields and purity. Researchers' active efforts to create open-source protocols for magnetic bead-based methods, fuel the segment growth.
Type Insight
The plasmid DNA isolation and purification segment is estimated to dominate the market. The demand for pure mRNA has surged owing to the growing usage of purified mRNA for the design of the cDNA library and the surge in use in COVID-19 diagnostics. There are several applications for these libraries, like sequencing, clinical diagnostics, and gene expression profiling. Additionally, the wide presence of kits for the extraction and processing of viral and bacterial RNA contributes the segment growth.
Application Insight
The drug discovery and development segment is estimated to dominate the market. This is due to the rapid technical innovation in the fields of genomics and proteomics and the development of cutting-edge therapeutics in the healthcare industry, such as gene therapy, antisense therapy, and DNA vaccines. The newly created techniques enable quick detection of pathogenic activity at the RNA and DNA level, leading to the identification of antimicrobial-resistant genes and genotyping-based strain characterization, further propelling the segment's expansion.
End-User Insight
The hospital and clinics segment dominated the market and is predicted to continue its dominance over the projection period. This can be attributed to the rising demand for precise and timely disease diagnosis. This segment is used in RNA/DNA isolation and purification techniques, genetic conditions such as hemophilia A, sickle cell anemia, and Tay-Sachs disease can even be diagnosed. Therefore, it is projected that the availability of such cutting-edge equipment at reasonable to low rates will improve the rate of adoption in diagnostic facilities and hospitals.
The pharmaceutical and biotechnology segment is estimated to increase significantly. The rapid utilization of innovative technologies for the development of several treatments by companies is predicted to create a positive impact on the market. As the first step in the manufacturing of many drugs and therapies, nucleic acid isolation and purification will surely promote the adoption of equipment and kits used in these procedures.
Prominent Companies
Segmentation Outline
The global nucleic acid isolation and purification market segmentation focuses on Product, Method, Type, Application, End-User, and Regions.
By Product
By Method
By Type
By Application
By End-User
By Region
[TABLE OF CONTENTS]
1 INTRODUCTION OF GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET
1.1 OVERVIEW OF THE MARKET
1.2 SCOPE OF REPORT
1.3 ASSUMPTIONS
2 EXECUTIVE SUMMARY: NUCLEIC ACID ISOLATION AND PURIFICATION MARKET
3 RESEARCH METHODOLOGY
3.1 DATA MINING
3.2 VALIDATION
3.3 PRIMARY INTERVIEWS
3.4 LIST OF DATA SOURCES
3.5 ANALYST TOOLS AND MODELS
4 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET OUTLOOK
4.1 OVERVIEW
4.2 MARKET DYNAMICS AND TRENDS
4.2.1 DRIVERS
4.2.2 RESTRAINTS
4.2.3 OPPORTUNITIES
4.3 PORTERS FIVE FORCE ANALYSIS
4.4 VALUE CHAIN ANALYSIS
4.5 MARKET GROWTH AND OUTLOOK
4.5.1 PRICE TREND ANALYSIS
4.5.2 OPPORTUNITY SHARE
5 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY PRODUCT
5.1 OVERVIEW
5.2 KITS AND REAGENTS
5.3 INSTRUMENTS
6 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY METHOD
6.1 OVERVIEW
6.2 COLUMN-BASED ISOLATION AND PURIFICATION
6.3 REAGENT-BASED ISOLATION AND PURIFICATION
6.4 MAGNETIC BEAD-BASED ISOLATION AND PURIFICATION
7 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY TYPE
7.1 OVERVIEW
7.2 PLASMID DNA ISOLATION AND PURIFICATION
7.3 TOTAL RNA ISOLATION AND PURIFICATION
7.4 GENOMIC DNA ISOLATION AND PURIFICATION
8 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY APPLICATION
8.1 OVERVIEW
8.2 DIAGNOSTICS
8.3 PRECISION MEDICINE
8.4 DRUG DISCOVERY AND DEVELOPMENT
8.5 AGRICULTURE AND ANIMAL RESEARCH
9 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY END-USER
9.1 OVERVIEW
9.2 HOSPITAL AND CLINICS
9.3 PHARMACEUTICAL AND BIOTECHNOLOGY
9.4 RESEARCH CENTERS AND GOVERNMENT INSTITUTES
10 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET, BY GEOGRAPHY
10.1 OVERVIEW
10.2 NORTH AMERICA
10.2.1 NORTH AMERICA MARKET SNAPSHOT
10.2.2 U.S.
10.2.3 CANADA
10.2.4 MEXICO
10.3 EUROPE
10.3.1 EUROPE MARKET SNAPSHOT
10.3.2 WESTERN EUROPE
10.3.2.1 THE UK
10.3.2.2 GERMANY
10.3.2.3 FRANCE
10.3.2.4 ITALY
10.3.2.5 SPAIN
10.3.2.6 REST OF WESTERN EUROPE
10.3.3 EASTERN EUROPE
10.3.3.1 POLAND
10.3.3.2 RUSSIA
10.3.3.3 REST OF EASTERN EUROPE
10.4 ASIA PACIFIC
10.4.1 ASIA PACIFIC MARKET SNAPSHOT
10.4.2 CHINA
10.4.3 JAPAN
10.4.4 INDIA
10.4.5 AUSTRALIA & NEW ZEALAND
10.4.6 ASEAN
10.4.7 REST OF ASIA PACIFIC
10.5 MIDDLE EAST & AFRICA
10.5.1 MIDDLE EAST & AFRICA MARKET SNAPSHOT
10.5.2 UAE
10.5.3 SAUDI ARABIA
10.5.4 SOUTH AFRICA
10.5.5 REST OF MEA
10.6 SOUTH AMERICA
10.6.1 SOUTH AMERICA MARKET SNAPSHOT
10.6.2 BRAZIL
10.6.3 ARGENTINA
10.6.4 REST OF SOUTH AMERICA
11 GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET COMPETITIVE LANDSCAPE
11.1 OVERVIEW
11.2 COMPANY MARKET RANKING
11.3 KEY DEVELOPMENT STRATEGIES
11.4 COMPETITIVE DASHBOARD
11.5 PRODUCT MAPPING
11.6 TOP PLAYER POSITIONING, 2022
11.7 COMPETITIVE HEATMAP
11.8 TOP WINNING STRATEGIES
12 COMPANY PROFILES
12.1 QIAGEN
12.1.1 OVERVIEW
12.1.2 FINANCIAL PERFORMANCE
12.1.3 PRODUCT OUTLOOK
12.1.4 KEY DEVELOPMENTS
12.1.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.2 ILLUMINA, INC
12.2.1 OVERVIEW
12.2.2 FINANCIAL PERFORMANCE
12.2.3 PRODUCT OUTLOOK
12.2.4 KEY DEVELOPMENTS
12.2.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.3 DANAHER
12.3.1 OVERVIEW
12.3.2 FINANCIAL PERFORMANCE
12.3.3 PRODUCT OUTLOOK
12.3.4 KEY DEVELOPMENTS
12.3.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.4 HOFFMANN-LA ROCHE LTD
12.4.1 OVERVIEW
12.4.2 FINANCIAL PERFORMANCE
12.4.3 PRODUCT OUTLOOK
12.4.4 KEY DEVELOPMENTS
12.4.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.5 MERCK KGAA
12.5.1 OVERVIEW
12.5.2 FINANCIAL PERFORMANCE
12.5.3 PRODUCT OUTLOOK
12.5.4 KEY DEVELOPMENTS
12.5.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.6 THERMO FISHER SCIENTIFIC, INC
12.6.1 OVERVIEW
12.6.2 FINANCIAL PERFORMANCE
12.6.3 PRODUCT OUTLOOK
12.6.4 KEY DEVELOPMENTS
12.6.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.7 AGILENT TECHNOLOGIES
12.7.1 OVERVIEW
12.7.2 FINANCIAL PERFORMANCE
12.7.3 PRODUCT OUTLOOK
12.7.4 KEY DEVELOPMENTS
12.7.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.8. BIO-RAD LABORATORIES, INC
12.8.1 OVERVIEW
12.8.2 FINANCIAL PERFORMANCE
12.8.3 PRODUCT OUTLOOK
12.8.4 KEY DEVELOPMENTS
12.8.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.9 GE HEALTHCARE
12.9.1 OVERVIEW
12.9.2 FINANCIAL PERFORMANCE
12.9.3 PRODUCT OUTLOOK
12.9.4 KEY DEVELOPMENTS
12.9.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.10 PROMEGA CORPORATION
12.10.1 OVERVIEW
12.10.2 FINANCIAL PERFORMANCE
12.10.3 PRODUCT OUTLOOK
12.10.4 KEY DEVELOPMENTS
12.10.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
12.11 NORGENBIOTEK CORP
12.11.1 OVERVIEW
12.11.2 FINANCIAL PERFORMANCE
12.11.3 PRODUCT OUTLOOK
12.11.4 KEY DEVELOPMENTS
12.11.5 KEY STRATEGIC MOVES AND DEVELOPMENTS
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